The Use Of Irrational Drug On Antibiotics And Off-Label Drugs From Industry Perspective:Article Review

IRMA RAHAYU LATARISSA, Norisca Aliza Putriana

Abstract


The World Health Organization (WHO) estimates that approximately 50% of all drug use is not appropriate in prescribing, preparing and selling. The inappropriate use of drugs will cause many problems. These issues include aspects of effectiveness, side effects, interactions, and economics. Rational use of drugs according to the WHO conference in Nairobi in 1985: when the patient receives treatment as clinical needed, dose as needed, time period was right, and a cost affordable to the patient's condition. Some cases of irrational use of drugs occur in the use of antibiotics and off-label drugs. One cause of irrational drug use is due to the cooperation between doctors as prescribing and pharmaceutical industry as a producer. In the pharmaceutical industry perspective, this will have an impact on the pharmaceutical profit industry, nowadays in Indonesia pay more attention to rational use of drugs (the right price indicator), supported by the current pharmaceutical era of health care shifted from money oriented or drug oriented to patient oriented.


Full Text:

PDF

References


World Health Organization. 2002. Promotional Rational Use of Medicines: Core Components, Geneva: World Health Organization.

Pharmaceutical Care Network Europe Foundation. 2003. Classification for Drug Related Problems. The Netherlands: PCNE, 5(1).

World Health Organization. 1985. The Ratonal Use of drugs Mexico : A case Study Conferenceof Experts On The Rasional Use of Drugs. Naiarobi, Kenya 25-29 November 1985, Geneva: World Health Organization

Sutradhar, K. B. 2014. Irrational Use of Antibiotics and Antibiotic Resistance in Southern Rural Bangladesh: Perspectives from Both the Physicians and Patients. Annual Research & Review in Biology, 1(1), pp.1-11.

Yewale, N. V., and Dhanya, D. 2012. Review Article Promoting Appropraiate Use of Drugs in Children. Hindawi Publishing Corporation International Journal of Pediatrics.

Casala, P. G., 2007. Executive Committee of ESMO, The Off-Label Use of Drugs in Oncology: A Position Paper by The European Society for Medical Oncology (ESMO). Ann Oncol, 18 (12), pp.1923-1925.

Corny J, Lebel D, Balley B. 2015. Unlicensed and Off-Label Drug Use in Children Before and After Pediatric Governmental Inutiatives. J Pediatr Pharmacol Ther. 20(4), pp. 316-328.

Hogerzeil, H. V., Ross-Degnan, D., Laing, R.O., Ofori-Adjei, D., Santoso, B., Chowdhury, A.K., Das, A.M., Kafle, K.K., Mabadeje, A.F.B., and Massele, A.Y. 1993. Field Test for Rational Drug Use in Twelve Developing Countries. The Lancet, pp.1408-1410.

Dwiprahasto, I., 2006. Peningkatan Mutu Penggunaan Obat di Puskesmas Melalui Pelatihan Berjenjang pada Dokter dan Perawat Jurnal Manajemen Pelayanan Kesehatan, 9 (2), pp.94-101.

Bergstrom, R. 2011. The Role of the Pharmaceutical Industry in Meeting the Public Health Threat of Antibacterial Resistance. Drug Resistance Updates, 14(1), pp.77–78.

Littmann, J. 2014. The Ethical Significance of Antimicrobial Resistance. Public Health Ethics. 8(3), pp.209–224.

Hassan , S.A.K., B.S. Hagnour. 2012. Rational Use of Medicine. Sudan Journal of Rational Use of Medicine, 1(2), pp.18-24.

Kartinah N, Dasupantini S dan Intannia D. 2013. Penggunaan obat Off-Label pada pasien Neonatus rawat Inap RSUD ULIN Banjarmasin Periode Januari-Desember 2013. Jurnal Pharmascience, 1 (1), pp. 23-27.

D. Cousins, A, Clarkson, S. Conroy, and I. Chonoonara, 2002. Medication Errors in children – An eight year review using press reports. Paedatric and Perinatal Drug Therapy, 5(2), pp. 52-58.

Tefera, Y.G., Gebresillassie, B.M., Mekuria, A.B., Abebe, T.B., Erku, D.A., Seid, N. and Beshir, H.B. 2017. Off‐label drug use in hospitalized children: a prospective observational study at Gondar University Referral Hospital, Northwestern Ethiopia. Pharmacology research & perspectives, 5(2).

S C, Shivhare, H.K Kunjwati, A. M. Manikrao, and A. V. Bondre. 2010. Drugs Hazards and rational use of drugs: a review. Journal of Chemical and Pharmaceurical Research, 2(1), pp. 106-112.

World Health Organization. 1993. How to Investigate Drug Use in Health Facilities. Geneva: World Health Organization.

Kementrian Kesehatan Republik Indonesia. 2011. Kurikulum Pelatihan Penggunaan Obat Rasional. Jakarta: Kemenkes RI

Reppe ,L.A., O. Spigset, and J. Schjott. 2016. Drug Information Services Today: Current Role and Future Perspectives in Rational Drug Therapy. Clinical Therapeutics, 1(1), pp. 1-8.




DOI: https://doi.org/10.24198/jf.v16i2.17488

DOI (PDF): https://doi.org/10.24198/jf.v16i2.17488.g8482

Article metrics

Abstract views : 0 | views : 0

Refbacks

  • There are currently no refbacks.


Copyright (c) 2018 IRMA RAHAYU LATARISSA, Norisca Aliza Putriana