Effect of Carrageenan as Gelling Agent on Tocopherol Acetate Emulgels

Meiti Rosmiati, Marline Abdassah, Anis Yohana Chaerunisaa

Abstrak


Vitamin E (Tocopherol acetate) is used in both oral and topical dosage.  The aim of  the research was to study  different concentration of Carrageenan, as gelling agent in Tocopherol acetate Emulgels.  This experimental study was initiated by emulgel formulation using different concentration of carrageenan as gelling agent, as much as 0,5% (F1), 0,75% (F2), 0,85% (F3), 0,95 % (F4), 1% (F5), 1,125% (F6), 1,25% (F7), 1,5% (F8) and 2% (F9).  Tween 20 and Span 20 were used as emulsifiers (1 and 1,5 %),  Liquid paraffin as oily phase (7,5%), Propylen glycol as humectant (10%), propyl and methyl paraben as antimicrobial preservative (0,01% and 0,03%). The physical investigation of emulgel were included pH, spreading test, viscosity and freeze thawtest. The results for promising formula F5 showed that physical parameters of emulgels were in the range of requirement for topical dosage form.

 

Keywords: Tocopherol acetate (Vitamin E), emulgels, carrageenan


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Referensi


Bakowska, Anna, dan Barczak. 2005. Acylated Anthocyanins As Stable, Natural Food Colorants – A Review. Polish Journal Of Food and Nutrition Sciences: 55(2): 107-116

Bechtold, T, & Rita Mussak. 2009. Handbook of Natural Colorants. United Kingdom: John Wiley & Sons Ltd.

Draelos, Z.D., dan Thaman, L.A. 2010. Cosmetic Formulation of Skin Care Products. New York: Taylor and Francis Group.

Ifesan, B. O., Siripongvutikorn, S., Hutadilok-Towatana, N., & Voravuthikunchai, S. P. 2009. Evaluation of the ability of Eleutherine americana crude extract asnatural food additive in cooked pork. Journal of Food Science, vol 74: 352-357.

Ifesan, B. O., Siripongvutikorn, S., & Voravuthikunchai, S. P. 2009. Application of Eleutherine americana crude extract in homemade salad dressing. Journal of Food Protection, vol 72: 650–655.

Ieyama, Tomohiro, Maria D. P. T. Gunawan Puteri, Jun Kawabata. Alfa-Glukosidase Inhibitor from Bulb of Eleutherine americana. Food Chemistry, vol 128: 308-311.

Kirca, Aysegul, Mehmet Ozkan, Bekir Cemeroglu. 2007. Effects of temperature, solid content and pH on the stability of black carrot anthocyanins. Food Chemistry, Vol. 101; 212-218.

Mitsui, T. 2007. New Cosmetic Science. Amsterdam: Elsevier.

Paramapojn, Sompol, Markus Ganzera, Wandee Gritsanapan, Hermann Stuppner. 2008. Journal of Pharmaceutical and Biomedical Analysis, vol. 47: 990-993.

Poucher, J., 2000. Poucher’s Perfumes, Cosmetics and Soaps, Edisi Kesepuluh. London: Kluwer Academic Publisher.




DOI: https://doi.org/10.24198/ijpst.v5i1.14280

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