Peran Flavonoid pada Berbagai Aktivitas Farmakologi

Izzatul Khoirunnisa, Sri Adi Sumiwi

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Flavonoid merupakan senyawa metabolit sekunder dengan struktur fenolik yang bervariasi dan dapat ditemukan dalam buah-buahan, sayuran, biji-bijian, kulit kayu, akar, batang, bunga, teh dan anggur. Flavonoid terkenal dengan efek menguntungkannya bagi kesehatan dan upaya sedang dilakukan untuk mengisolasi bahan yang disebut flavonoid. Flavonoid sekarang dianggap sebagai komponen yang sangat diperlukan dalam berbagai aplikasi nutrasetikal, farmasi, obat-obatan dan kosmetik. Hal ini karena flavonoid memiliki sifat antioksidan, anti-inflamasi, anti-mutagenik dan anti-karsinogenik ditambah dengan kapasitasnya untuk memodulasi seluler kunci fungsi enzim. Saat ini banyak dilakukan kegiatan penelitian dan pengembangan flavonoid terkait dengan isolasi, identifikasi, karakterisasi dan fungsi flavonoid dan akhirnya penerapannya pada manfaat kesehatan. Dalam review ini dibahas mengenai 26 jenis flavonoid beserta aktivitas farmakologis dari flavonoid tersebut.


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DOI: https://doi.org/10.24198/jf.v17i2.21922

DOI (PDF): https://doi.org/10.24198/jf.v17i2.21922.g11628

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