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Email this article Antibacterial potential of celery leaf extract toothpaste on the growth of Streptococcus mutans ATCC 25175
Abstract
ABSTRACT
Introduction: Celery (Apium graveolens L.) is a member of the Apiaceae family that can grow everywhere. Celery contains flavonoids, saponins, tannins, essential oils, apigenin, choline, vitamins A, B, C, asparagine bitter substances. Celery contains flavonoids, saponins, and tannins which are antibacterial compounds. Streptococcus mutans is a Gram-positive bacterium creating an acidic atmosphere in the oral cavity, which causes insufficient saliva to prevent enamel demineralisation which can lead to dental caries. The purpose of this study was to analyze the inhibition effect of celery leaf extract (Apium graveolens L.) on the growth of Streptococcus mutans. Methods: This type of experimental laboratory research uses the Post Test Only Control Group Design. The samples were Apium graveolens L. and Streptococcus mutans ATCC 25175. The number of treatment groups was 24 with concentrations of 20, 40, 60, and 80%. Toothpaste containing antibacterial ingredients was used as positive control and for negative control, a basic toothpaste formula without antibacterial ingredients, namely carboxymethyl cellulose (CMC), xylitol, calcium carbonate (CaCO3), sorbitol, sodium lauryl sulphate (SLS), natrium benzoate. Data analysis using one-way ANOVA test with normality test using Shapiro-Wilk and homogeneity test using Levene test. The results at a concentration of 20, 40, 60 and 80% with a positive control there was no significant difference because the sig value was >0.05. Results: The results showed that Celery containing toothpaste inhibits Streptococcus mutans growth (p value <0.05) that there is a significant inhibition effect of Apium graveolens L. extract toothpaste on the growth of Streptococcus mutans. Conclusion: There is an inhibition effect of celery leaf (Apium graveolens L.) extract toothpaste on the growth of Streptococcus mutans.
Keywords: streptococcus mutans ATCC 25175, inhibition, toothpaste, celery, apium graveolens L
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REFERENCES
Riskesdas. Main Results of Riskesdas for Dental and Oral Health. National Health Center. 2018. p. 5.
Alfath CR, Yulina V, Sunnati. Antibacterial effect of granati fructus cortex extract on Sreptococcus mutans in vitro. J Dent Ind. 2013; 20(1); 5-8. DOI: 10.14693/jdi.v20i1.126
Kidd EAM, Bechal SJ. The Basics of Caries Disease and Its Management. Jakarta: EGC. 2013. p. 109-161
Putri MH, Herijulianti E, Nurjannah N. Disease Prevention Science of Dental Hard Tissue and Supporting Tissue. Jakarta: EGC; 2010. p. 111-112
Jawetz E, Melnick JL, Adelberg EA. Medical Microbiology. 27th Edition. 2016. Hal 237
Sowbhagya HB. Chemistry, Technology, and Nutraceutical Functions of Celery (Apium Graveolens L.): An Overview. Crit Rev Food Sci and Nut. 2014; 54(3); 389-398. DOI: 10.1080/10408398.2011.586740
Majidah D, Fatmawati DWA, Gunadi A. Antibacterial Power of Celery Leaf Extract (Apium graveolens L.) on the Growth of Streptococcus mutans as an Alternative Mouthwash. Repository WIMA. 2014; 1-5.
Suwito MB, Wahyunitisari MR, Umijati S. The Effectiveness of Celery Extract (Apium graveolens L. var. secalinum Alef.) Against the Growth of Streptococcus mutans as an Alternative Mouthwash. J Ked Syiah Kuala. 2017; 7(3); 159-163. DOI: 10.24815/jks.v17i3.9150
Donald R. Nahusona, Felisia YT. Effect of celery leaves extract on the growth of Candida albicans in patients wearing removable orthodontic appliances. 2020. 9(3): 163-166. DOI: 10.35856/mdj.v9i3.345
Astuti RD, Khotimah S. Patch Formulation of Celery Leaves Extract (Apium Graveolens L.) As Mosquito Repellent. Journal Advances in Social Science, Education and Humanities Research. 2021; 52(1).
Bhattacharjee S. Nath S, Bhattacharjee P, Chouhan M. Efficacy of Toothpastes on Bacteria Isolated from Oral Cavity. A Multifaceted Peer Reviewed Journal in the field of Medicine and Public Health. 2018; 8(2); 89-92. DOI:10.5530/ijmedph.2018.2.19
Yuliastri OW, Ifaya M, Prasetyo M. Formulation of Herbal Toothpaste Breadfruit Leaf Extract (Artocarpus altilis) And Antibacterial Activity Test Against Streptococcus mutans bacteria. J Mandala Pharmacon Ind. 2019; 5(1). DOI: 10.35311/jmpi.v5i01.35
Ranganathan V, Akhila CH. 2019. Streptococcus mutans: has it become prime perpetrator for oral manifestations?. J Microbiol Exp. 2019; 7(4); 207-213. DOI: 10.15406/jmen.2019.07.00261
Rusdiana T. Study of Celery (Apium Graveolens L.) As a Natural Source of High Potential Ingredients in Health Promotion Efforts. Ind Natural Research Pharmaceutical J. 2018; 3(1). DOI: 10.52447/inspj.v3i1.874
Susi, Bachtiar H, Sali N. Differences In Inhibitory Power Of Herbal Toothpaste On The Growth Of Streptococcus Mutants. J MKA. 2015; 38(2); 116-123. DOI: 10.22338/mka.v38.i2.p116-123.2015
DOI: https://doi.org/10.24198/pjd.vol35no1.30624
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